Which phase follows inflammation in wound healing?

In wound healing, the phase that follows inflammation is the proliferation phase. During this phase, the body focuses on tissue formation and healing. It involves several key processes, including the formation of granulation tissue, re-epithelialization, and the initial healing of the wound.

During inflammation, the body responds to injury by increasing blood flow to the area, influx of immune cells, and secretion of various cytokines to manage the healing process. Once this acute inflammatory response subsides, the proliferation phase takes over to rebuild the tissue.

One important aspect of this phase is the formation of granulation tissue, which consists of new connective tissue and blood vessels that emerge at the site of the wound. This tissue provides a scaffold for new cells and promotes healing. Additionally, fibroblasts proliferate and synthesize collagen and extracellular matrix components, aiding in the structural integrity of the new tissue.

Thus, the proliferation phase is crucial for repairing the wound and restoring the integrity of the skin or affected tissue following the inflammatory phase.